Regular and NPH insulins with delayed action can be mixed. The resulting NPH mixes insulins can be adapted to the individual needs of a diabetic. The pharmacodynamics of both components will stay the same.
NPH-mixed insulins are available in different defined relations also in ready injection pens.
Mixed analogues are ready mixtures from short-acting insulin analogues and a component with delayed action. The short-acting part covers the insulin need for meals whereas the component with delayed action takes care for basal needs. Mixes analogues can be injected direct at the meal and the risk to develop a hypoglycaemia is reduced. Blood glucose levels after the meal are better in comparison to injections of mixed insulins containing regular insulin.